Answer
Parents of a child with ARPKD have a 1 in 4 chance of conceiving another child with the disease, and a 1 in 2 chance of being a carrier of the disease. Carriers of the ARPKD gene typically do not experience any symptoms of the disease. Prenatal diagnosis of ARPKD is possible in at-risk families through genetic testing. ARPKD does not directly involve the reproductive system, and having the disease does not decrease the changes of having children, however it can pose potential risks complications, leading to a decreased likelihood of a successful pregnancy.
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