Healthy Diet, Intermittent Fasting and PKD
This session consisted of two parts:
(1) Lecture (20 minutes and 10 minutes Q&A): Review: (i) recent preclinical studies of novel dietary intervention (e.g. caloric restriction, ketotic diet) in slowing experimental PKD progression; (ii) elements of a healthy diet; (iii) potential utility of intermittent fasting or time-restricted feeding for clinical treatment of ADPKD.
(2) Practical advice for a healthy diet by a registered RD and Open forum for Q&A (30 minutes).
Senior Scientist, Toronto General Hospital Research Institute (TGHRI)
Nephrologist, Toronto General Hospital, University Health Network
Dr. Pei is a Professor of Medicine at the University of Toronto. He is also a staff nephrologist at the Toronto General Hospital, University Health Network, where he directs the Center for Innovative Management for Polycystic Kidney Disease (https://www.cimpkd.ca/our-team.html). He received research training in both Clinical Epidemiology and Human Molecular Genetics. His research program focuses on genetic, genomic, and translational research of hereditary kidney diseases with a major focus on autosomal dominant polycystic kidney disease and is supported by grants from the Kidney Foundation of Canada, Physicians Incorporated Foundation, Polycystic Kidney Disease Foundation (USA), and Canadian Institutes of Health Research. He has published more than 150 peer-reviewed papers and had had served in the Editorial Board for the Journal of American Society of Nephrology and Grant Review Panels for the Kidney Foundation of Canada, Canadian Institutes of Health Research, PKD foundation (USA), and National Institutes of Health, USA. He was a co-recipient of the 2019 Lillian J. Kaplan International Prize for Advancement in the Understanding of Polycystic Kidney Disease (https://www.theisn.org/about-isn/awards-a-prizes/lillian-jean-kaplan-international-prize).
Dr. Weimbs received his doctoral degree from the Department of Biochemistry of the University of Cologne, Germany, in 1993. He conducted postdoctoral research at the Department of Anatomy, University of California at San Francisco until 1999. In the same year, he joined the Department of Cell Biology in the Lerner Research Institute of the Cleveland Clinic as an Assistant Professor where he established his research laboratory focusing on investigating membrane trafficking and epithelial cell polarity as well as molecular mechanisms underlying polycystic kidney disease. In 2005, Dr. Weimbs was recruited to the Department of Molecular, Cellular, and Developmental Biology and moved his laboratory to UCSB. Dr. Weimbs is currently an Associate Professor in MCDB and in the Neuroscience Research Institute.
Hoon-Ki Sung PhD
Dr Sung received his M.D. from South Korea in 1997. In 2004, he obtained his Ph.D. in the Department of Clinical Oriented Anatomy and Functional Histology, University of Yeungnam. Following his Ph.D., he did his postdoctoral research at the Korea Advanced Institute of Science and Technology (KAIST) in the laboratory of Dr Gou Young Koh. In 2006, he moved to Toronto and joined the laboratory of Dr Andras Nagy in the Tanenbaum-Lunenfeld Research Institute at Mount Sinai Hospital. In 2014, he established his laboratory in the Physiology and Experimental Medicine Program at the Hospital for Sick Children Research Institute. His main research interest includes adipose biology and metabolism, angiogenesis and stem cell.